| NCT03365479 |
Acute Response of Iloprost Inhalation Using the Breelib Nebulizer in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03365479 |
Completed |
University of Giessen |
2018-08-01 |
| NCT04273945 |
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT04273945 |
Recruiting |
Actelion |
2023-10-31 |
| NCT03904693 |
Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT03904693 |
Recruiting |
Actelion |
2023-12-15 |
| NCT03492177 |
A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03492177 |
Recruiting |
Actelion |
2026-02-11 |
| NCT03399604 |
Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil |
https://ClinicalTrials.gov/show/NCT03399604 |
Active, not recruiting |
Liquidia Technologies, Inc. |
2019-05-06 |
| NCT03315507 |
A Study to Assess the Safety, Tolerability, and Hemodynamic Response of PB1046 in Subjects With PAH |
https://ClinicalTrials.gov/show/NCT03315507 |
Completed |
PhaseBio Pharmaceuticals Inc. |
2019-08-08 |
| NCT03288025 |
Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE) |
https://ClinicalTrials.gov/show/NCT03288025 |
Recruiting |
The Cleveland Clinic |
2022-12-28 |
| NCT03251872 |
Olaparib for PAH: a Pilot Study |
https://ClinicalTrials.gov/show/NCT03251872 |
Recruiting |
Laval University |
2019-12-31 |
| NCT03205085 |
Determinants of Right Heart Remodeling in Patients With CTEPH or PAH |
https://ClinicalTrials.gov/show/NCT03205085 |
Recruiting |
Centre Chirurgical Marie Lannelongue |
2020-07-01 |
| NCT03187678 |
Safety Study of the Switch From Oral Selexipag to Intravenous Selexipag in Subjects With Stable Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03187678 |
Completed |
Actelion |
2018-05-29 |
| NCT03166306 |
Angiogenic Imaging in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03166306 |
Recruiting |
Brigham and Women’s Hospital |
2019-10-31 |
| NCT03145298 |
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy |
https://ClinicalTrials.gov/show/NCT03145298 |
Recruiting |
Cedars-Sinai Medical Center |
2020-01-01 |
| NCT03105934 |
Repeatability of OCT and IV-US in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03105934 |
Completed |
Hospital Universitari Vall d’Hebron Research Institute |
2017-10-18 |
| NCT03078907 |
Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension. |
https://ClinicalTrials.gov/show/NCT03078907 |
Completed |
Actelion |
2020-02-10 |
| NCT03069716 |
A Mobile Health Intervention in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03069716 |
Active, not recruiting |
Vanderbilt University Medical Center |
2020-06-30 |
| NCT03057028 |
Pilot Study of the Safety and Efficacy of Anakinra in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03057028 |
Completed |
Virginia Commonwealth University |
2018-06-07 |
| NCT03055221 |
TRUST-2: Safety and Efficacy of Intravenous Remodulin® in Patients in India With Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT03055221 |
Completed |
United Therapeutics |
2014-02-25 |
| NCT02932410 |
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT02932410 |
Recruiting |
Actelion |
2022-07-14 |
| NCT02911844 |
Estrogen Receptor Antagonist in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02911844 |
Completed |
University of Pennsylvania |
2018-12-05 |
| NCT02891850 |
Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy |
https://ClinicalTrials.gov/show/NCT02891850 |
Completed |
Bayer |
2020-01-29 |
| NCT02859194 |
The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients |
https://ClinicalTrials.gov/show/NCT02859194 |
Completed |
Yonsei University |
2016-10-14 |
| NCT02847260 |
Safety and Tolerability of Rapid Dose Titration of Subcutaneous Remodulin® Therapy in PAH Subjects (RAPID) |
https://ClinicalTrials.gov/show/NCT02847260 |
Completed |
United Therapeutics |
2014-03-31 |
| NCT02790450 |
Acute Effects of Benzbromaron on the Pulmonary Circulation |
https://ClinicalTrials.gov/show/NCT02790450 |
Completed |
Medical University of Graz |
2016-08-31 |
| NCT02734953 |
Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH |
https://ClinicalTrials.gov/show/NCT02734953 |
Completed |
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) |
2016-08-31 |
| NCT02676947 |
A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02676947 |
Completed |
Papworth Hospital NHS Foundation Trust |
2018-02-18 |
| NCT02664558 |
A Study of Ubenimex in Patients With Pulmonary Arterial Hypertension (WHO Group 1) |
https://ClinicalTrials.gov/show/NCT02664558 |
Completed |
Eiger BioPharmaceuticals |
2017-11-30 |
| NCT03626688 |
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients |
https://ClinicalTrials.gov/show/NCT03626688 |
Recruiting |
United Therapeutics |
2021-12-31 |
| NCT00098072 |
Endothelial Cell Dysfunction in Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT00098072 |
Completed |
National Institutes of Health Clinical Center (CC) |
2009-07-08 |
| NCT02558231 |
The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02558231 |
Active, not recruiting |
Actelion |
2019-08-29 |
| NCT02551653 |
Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) Patients |
https://ClinicalTrials.gov/show/NCT02551653 |
Completed |
GlaxoSmithKline |
2017-03-14 |
| NCT02471183 |
Study to Assess the Tolerability and the Safety of the Transition From Inhaled Treprostinil to Oral Selexipag in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02471183 |
Completed |
Actelion |
2016-12-05 |
| NCT02371733 |
Aerobic Exercise Training in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02371733 |
Completed |
Gazi University |
2018-01-31 |
| NCT02310672 |
REPAIR: Right vEntricular Remodeling in Pulmonary ArterIal hypeRtension |
https://ClinicalTrials.gov/show/NCT02310672 |
Completed |
Actelion |
2019-09-10 |
| NCT02304198 |
Clinical Trial to Evaluate the Long-term Safety of Udenafil in Patient With PAH |
https://ClinicalTrials.gov/show/NCT02304198 |
Completed |
Dong-A ST Co., Ltd. |
2016-02-29 |
| NCT02279745 |
Long Term Safety and Efficacy of Ralinepag in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02279745 |
Active, not recruiting |
United Therapeutics |
2020-08-31 |
| NCT02279160 |
Safety and Efficacy of APD811 in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02279160 |
Completed |
Arena Pharmaceuticals |
2017-06-30 |
| NCT02234141 |
Selonsertib in Adults With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02234141 |
Completed |
Gilead Sciences |
2016-04-30 |
| NCT02223481 |
Safety and Efficacy of Terbogrel in Patients With Primary Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT02223481 |
Completed |
Boehringer Ingelheim |
1999-09-30 |
| NCT02112487 |
Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH |
https://ClinicalTrials.gov/show/NCT02112487 |
Completed |
Actelion |
2018-09-19 |
| NCT02080533 |
Feasibility of Slow-paced Respiration Therapy for Treatment of a Symptom Cluster in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02080533 |
Completed |
University of Pennsylvania |
2015-03-31 |
| NCT02060487 |
Effects of Oral Sildenafil on Mortality in Adults With PAH |
https://ClinicalTrials.gov/show/NCT02060487 |
Recruiting |
Pfizer |
2023-06-30 |
| NCT02032836 |
Comparative PK PD Study in PAH Patients (Fox vs. I-Neb) |
https://ClinicalTrials.gov/show/NCT02032836 |
Completed |
Bayer |
2015-01-07 |
| NCT02000856 |
BEET PAH: a Study to Assess the Effects of Beetroot Juice in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02000856 |
Completed |
Uppsala University |
2015-02-28 |
| NCT01966302 |
Compassionate Use of Beraprost Sodium 314d Modified Release for Patients With Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT01966302 |
Completed |
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center |
2019-06-02 |
| NCT01908699 |
Beraprost-314d Added-on to Tyvaso® (BEAT) |
https://ClinicalTrials.gov/show/NCT01908699 |
Completed |
Lung Biotechnology PBC |
2019-02-19 |
| NCT01841762 |
Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument |
https://ClinicalTrials.gov/show/NCT01841762 |
Completed |
Actelion |
2015-11-01 |
| NCT01757808 |
A Study of Ranolazine Acute Administration and Short Term Administration in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01757808 |
Completed |
University of Chicago |
2015-01-31 |
| NCT01712620 |
Spironolactone for Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01712620 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2021-10-01 |
| NCT01647945 |
FK506 (Tacrolimus) in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01647945 |
Completed |
Stanford University |
2014-05-31 |
| NCT01642407 |
Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01642407 |
Completed |
Pfizer |
2016-05-20 |
| NCT01613287 |
Proof of Concept Study of IMMUNOadsorption Therapy in Patients With Idiopathic Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01613287 |
Completed |
Miltenyi Biotec B.V. & Co. KG |
2013-08-31 |
| NCT01590108 |
The Study of Apelin-APJ System on Pulmonary Hypertension Patients and Healthy Subjects |
https://ClinicalTrials.gov/show/NCT01590108 |
Completed |
Imperial College London |
2014-09-30 |
| NCT01588405 |
Remodulin® to Oral Treprostinil Transition |
https://ClinicalTrials.gov/show/NCT01588405 |
Completed |
United Therapeutics |
2014-07-31 |
| NCT01572077 |
Rt Ventricular Substrate Metabolism as a Predictor of Rt Heart Failure in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01572077 |
Completed |
Ottawa Heart Institute Research Corporation |
2016-12-31 |
| NCT01560637 |
An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01560637 |
Active, not recruiting |
United Therapeutics |
2021-05-31 |
| NCT01560624 |
Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy |
https://ClinicalTrials.gov/show/NCT01560624 |
Completed |
United Therapeutics |
2018-06-24 |
| NCT01557582 |
Assessmet of Patients With PAH Right Ventricular Volume |
https://ClinicalTrials.gov/show/NCT01557582 |
Completed |
VentriPoint Diagnostics Ltd. |
2013-11-30 |
| NCT01553721 |
Efficacy and Safety Study of Udenafil in Patient With Pulmonary Arterial Hypertension(PAH) |
https://ClinicalTrials.gov/show/NCT01553721 |
Completed |
Dong-A ST Co., Ltd. |
2015-03-31 |
| NCT01548950 |
Drug Therapy and Surgery in Congenital Heart Disease With Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT01548950 |
Completed |
University of Sao Paulo General Hospital |
2014-01-31 |
| NCT01545336 |
Anastrozole in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01545336 |
Completed |
University of Pennsylvania |
2015-06-30 |
| NCT01520493 |
Peripheral Muscle Microcirculation and Exercise-induced Blood Flow Distribution in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01520493 |
Completed |
Laval University |
2013-08-31 |
| NCT01484431 |
A Pharmacokinetics Study for Pediatric Participants With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01484431 |
Completed |
Eli Lilly and Company |
2017-04-21 |
| NCT01477333 |
Addition of UT-15C SR to Pulmonary Arterial Hypertension Patients Currently Receiving Tyvaso® |
https://ClinicalTrials.gov/show/NCT01477333 |
Completed |
United Therapeutics |
2013-11-30 |
| NCT01470144 |
Epoprostenol for Injection in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01470144 |
Completed |
Actelion |
2015-06-01 |
| NCT01461343 |
Evaluation of Pulmonary Perfusion Heterogeneity and Compliance in Patients With Pulmonary Hypertension Using Positron Emission Tomography Imaging |
https://ClinicalTrials.gov/show/NCT01461343 |
Completed |
Massachusetts General Hospital |
2017-11-21 |
| NCT01457781 |
Inhaled Nitric Oxide/INOpulse DS for Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT01457781 |
Completed |
Bellerophon |
2014-10-31 |
| NCT01447628 |
IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients |
https://ClinicalTrials.gov/show/NCT01447628 |
Completed |
Imperial College London |
2017-12-22 |
| NCT01431716 |
Epoprostenol for Injection (EFI/ACT-385781A) - Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01431716 |
Completed |
Actelion |
2012-02-29 |
| NCT01409122 |
Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects |
https://ClinicalTrials.gov/show/NCT01409122 |
Completed |
Aires Pharmaceuticals, Inc. |
2012-01-31 |
| NCT01397110 |
Respiratory and Physical Therapy in Patients With Associated Pulmonary Arterial Hypertension (APAH) With Congenital Heart Defects |
https://ClinicalTrials.gov/show/NCT01397110 |
Recruiting |
Heidelberg University |
2025-12-31 |
| NCT01392469 |
Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension Patients |
https://ClinicalTrials.gov/show/NCT01392469 |
Completed |
Novartis |
2012-10-25 |
| NCT01391104 |
Responsiveness of Exercise Tests in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01391104 |
Completed |
Laval University |
2011-11-30 |
| NCT01338636 |
An Open-Label Uncontrolled Study of the Safety and Efficacy of Ambrisentan in Participants With Exercise-Induced Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT01338636 |
Completed |
Brigham and Women’s Hospital |
2016-02-29 |
| NCT01338415 |
FUTURE 3 Study Extension |
https://ClinicalTrials.gov/show/NCT01338415 |
Active, not recruiting |
Actelion |
2014-08-13 |
| NCT01321073 |
DelIVery for Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT01321073 |
Active, not recruiting |
Medtronic Cardiac Rhythm and Heart Failure |
2013-06-30 |
| NCT03528902 |
Tamoxifen Therapy to Treat Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03528902 |
Recruiting |
Vanderbilt University Medical Center |
2022-06-30 |
| NCT04316143 |
Pharmacokinetics, Safety and Efficacy of BIA 5-1058 in PAH |
https://ClinicalTrials.gov/show/NCT04316143 |
Recruiting |
Bial - Portela C S.A. |
2020-08-31 |
| NCT04125745 |
Oral CXA-10 in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT04125745 |
Active, not recruiting |
University of Pittsburgh |
2023-06-30 |
| NCT04062565 |
Trial to Evaluate Parenteral Treprostinil and Riociguat on Right Ventriculo-vascular Coupling and Morphology in Those With Advanced PAH |
https://ClinicalTrials.gov/show/NCT04062565 |
Recruiting |
University of Arizona |
2020-12-31 |
| NCT03992755 |
Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil |
https://ClinicalTrials.gov/show/NCT03992755 |
Active, not recruiting |
Liquidia Technologies, Inc. |
2021-12-31 |
| NCT03950739 |
Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso |
https://ClinicalTrials.gov/show/NCT03950739 |
Recruiting |
United Therapeutics |
2020-05-31 |
| NCT03926793 |
Clinical Study of Inhaled GB002 for Treatment of WHO Group I Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03926793 |
Recruiting |
Gossamer Bio Inc. |
2020-06-30 |
| NCT03905083 |
miRNA and Myokines in Patients With PAH |
https://ClinicalTrials.gov/show/NCT03905083 |
Recruiting |
University of Pittsburgh |
2022-03-15 |
| NCT03884465 |
Hemodynamic Evaluation of Dose-response and Safety of Dry Powder Inhalation of Treprostinil |
https://ClinicalTrials.gov/show/NCT03884465 |
Active, not recruiting |
Liquidia Technologies, Inc. |
2020-11-30 |
| NCT03841344 |
Repeatability and Sensitivity to Change of Non-invasive Endpoints in PAH |
https://ClinicalTrials.gov/show/NCT03841344 |
Active, not recruiting |
University of Sheffield |
2018-09-24 |
| NCT03795428 |
Long-Term, Open Label Extension Study of PB1046 in PAH Subjects Following Completion of Study PB1046-PT-CL-0004 |
https://ClinicalTrials.gov/show/NCT03795428 |
Recruiting |
PhaseBio Pharmaceuticals Inc. |
2024-01-15 |
| NCT03782818 |
Olaparib for PAH: a Multicenter Clinical Trial |
https://ClinicalTrials.gov/show/NCT03782818 |
Recruiting |
Laval University |
2021-11-12 |
| NCT03744637 |
A Study of Single Doses of MK -5475 on Pulmonary Vascular Resistance (MK-5475-002) |
https://ClinicalTrials.gov/show/NCT03744637 |
Recruiting |
Merck Sharp & Dohme Corp. |
2021-02-05 |
| NCT03683082 |
Oxygen Treatment and Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03683082 |
Recruiting |
George Papanicolaou Hospital |
2019-06-10 |
| NCT03657095 |
BPS-314d-MR-PAH-303 (BEAT OLE) |
https://ClinicalTrials.gov/show/NCT03657095 |
Completed |
Lung Biotechnology PBC |
2019-07-20 |
| NCT03655704 |
Apabetalone for Pulmonary Arterial Hypertension: a Pilot Study |
https://ClinicalTrials.gov/show/NCT03655704 |
Recruiting |
Laval University |
2020-06-30 |
| NCT03638908 |
Fluoxetine in Pulmonary Arterial Hypertension (PAH) Trial |
https://ClinicalTrials.gov/show/NCT03638908 |
Completed |
University of Texas Southwestern Medical Center |
2017-05-31 |
| NCT03554330 |
Combined Use of Radiofrequency-ablation and Balloon-septostomy in the Creation of a Stable Inter-atrial Communication |
https://ClinicalTrials.gov/show/NCT03554330 |
Recruiting |
China National Center for Cardiovascular Diseases |
2020-12-30 |
| NCT03497689 |
EXPEDITE: A Study of Remodulin Induction Followed by Orenitram Optimization to Treat Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03497689 |
Recruiting |
United Therapeutics |
2020-07-31 |
| NCT03496207 |
A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT03496207 |
Active, not recruiting |
Acceleron Pharma, Inc. |
2020-03-31 |
| NCT03422328 |
A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Arterial Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. |
https://ClinicalTrials.gov/show/NCT03422328 |
Enrolling by invitation |
Actelion |
2021-04-03 |
| NCT01265888 |
Study in Subjects With PAH and PH Secondary to IPF Using Inhaled GeNOsyl. |
https://ClinicalTrials.gov/show/NCT01265888 |
Completed |
Geno LLC |
2016-09-30 |
| NCT01223352 |
Effects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01223352 |
Completed |
Actelion |
2013-04-03 |
| NCT01208792 |
Auto-immunity and Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01208792 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2014-07-15 |
| NCT01174173 |
Ranolazine and Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT01174173 |
Completed |
Northwestern University |
2014-01-31 |
| NCT01148836 |
Coenzyme Q-10 and Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01148836 |
Completed |
The Cleveland Clinic |
2014-01-31 |
| NCT01112306 |
ACT-293987 in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01112306 |
Active, not recruiting |
Actelion |
2020-12-31 |
| NCT01106014 |
Selexipag (ACT-293987) in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01106014 |
Completed |
Actelion |
2014-04-01 |
| NCT01105117 |
Epoprostenol for Injection in Pulmonary Arterial Hypertension - Extension of AC-066A401 |
https://ClinicalTrials.gov/show/NCT01105117 |
Completed |
Actelion |
2011-07-31 |
| NCT01105091 |
Epoprostenol for Injection in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01105091 |
Completed |
Actelion |
2011-05-31 |
| NCT01042158 |
A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01042158 |
Completed |
Johns Hopkins University |
2014-11-30 |
| NCT01027949 |
An Open-Label Extension Trial of UT-15C SR in Subjects With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01027949 |
Active, not recruiting |
United Therapeutics |
2020-12-31 |
| NCT00993408 |
Study of ACT-293987 (NS-304) in Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT00993408 |
Completed |
Actelion |
2009-06-30 |
| NCT00990314 |
Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) Patients |
https://ClinicalTrials.gov/show/NCT00990314 |
Completed |
Lung Biotechnology PBC |
2013-11-30 |
| NCT00989963 |
Dose-response Study of the Safety and Efficacy of Beraprost Sodium Modified Release (BPS-MR) in Patients With Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT00989963 |
Completed |
Lung Biotechnology PBC |
2011-12-31 |
| NCT00964678 |
Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00964678 |
Completed |
Virginia Commonwealth University |
2014-05-31 |
| NCT00942708 |
Safety and Efficacy of Fluoxetine in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00942708 |
Completed |
University of Texas Southwestern Medical Center |
2011-06-30 |
| NCT00902174 |
Imatinib (QTI571) in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00902174 |
Completed |
Novartis |
2011-05-31 |
| NCT01926509 |
Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-005) |
https://ClinicalTrials.gov/show/NCT01926509 |
Completed |
Merck Sharp & Dohme Corp. |
2014-09-01 |
| NCT03612115 |
Neuromuscular Electrical Stimulation in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03612115 |
Completed |
Dokuz Eylul University |
2017-09-28 |
| NCT03282266 |
Safety and Efficacy of Pulmonary Artery Denervation in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03282266 |
Recruiting |
Nanjing First Hospital, Nanjing Medical University |
2021-07-30 |
| NCT02961023 |
The Effect of Adding Exercise Training to Optimal Therapy in PAH |
https://ClinicalTrials.gov/show/NCT02961023 |
Completed |
National Health Service, United Kingdom |
2018-07-31 |
| NCT02579954 |
Cardiac Function and Exercise Capacity in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02579954 |
Recruiting |
Centre Hospitalier Universitaire de Saint Etienne |
2020-12-31 |
| NCT03683186 |
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension |
https://ClinicalTrials.gov/show/NCT03683186 |
Enrolling by invitation |
United Therapeutics |
2024-09-30 |
| NCT03738150 |
A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT03738150 |
Recruiting |
Acceleron Pharma, Inc. |
2021-12-31 |
| NCT00792571 |
An Open-Label Extension of BPS-MR-PAH-201 in Pulmonary Arterial Hypertension (PAH) Patients |
https://ClinicalTrials.gov/show/NCT00792571 |
Completed |
Lung Biotechnology PBC |
2013-11-30 |
| NCT00741819 |
Safety Evaluation of Inhaled Treprostinil Administration Following Transition From Inhaled Ventavis in Pulmonary Arterial Hypertension (PAH) Subjects |
https://ClinicalTrials.gov/show/NCT00741819 |
Completed |
United Therapeutics |
2010-03-31 |
| NCT00709956 |
Iloprost Power 15 in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00709956 |
Completed |
Actelion |
2009-08-31 |
| NCT00709098 |
Safety Study Extension of Iloprost Power 15 in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00709098 |
Completed |
Actelion |
2010-06-30 |
| NCT00705133 |
Treprostinil Therapy For Patients With Interstitial Lung Disease And Severe Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00705133 |
Completed |
University of California, Los Angeles |
2011-01-31 |
| NCT00667823 |
Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00667823 |
Active, not recruiting |
Actelion |
2020-06-30 |
| NCT00660179 |
Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00660179 |
Completed |
Actelion |
2012-03-31 |
| NCT00641836 |
Safety and Feasibility of Autologous Endothelial Progenitor Cells Transplantation in Patients With Idiopathic Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00641836 |
Completed |
Zhejiang University |
NA |
| NCT00626028 |
Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing |
https://ClinicalTrials.gov/show/NCT00626028 |
Completed |
Mallinckrodt |
2010-02-28 |
| NCT00617305 |
Study of Add-on Ambrisentan Therapy to Background Phosphodiesterase Type-5 Inhibitor (PDE5i) Therapy in Pulmonary Arterial Hypertension (ATHENA-1) |
https://ClinicalTrials.gov/show/NCT00617305 |
Completed |
Gilead Sciences |
2011-02-28 |
| NCT00609349 |
The Early Recognition of Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00609349 |
Completed |
Medical University of Graz |
2009-05-31 |
| NCT00578786 |
A Long Term Study of Ambrisentan in Pulmonary Arterial Hypertension Subjects Having Completed AMB-320 (NCT00423748) or AMB-321 (NCT00423202) |
https://ClinicalTrials.gov/show/NCT00578786 |
Completed |
Gilead Sciences |
2010-03-31 |
| NCT00566423 |
Biomarkers in the Diagnosis and Assessment of Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT00566423 |
Completed |
Northwell Health |
2008-05-31 |
| NCT00554619 |
A Study to Evaluate GSK1325760A - a Long-Term Extension Study |
https://ClinicalTrials.gov/show/NCT00554619 |
Completed |
GlaxoSmithKline |
2011-01-31 |
| NCT00477269 |
Safety and Efficacy of Imatinib Mesylate in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00477269 |
Completed |
Novartis |
2014-01-31 |
| NCT00452218 |
Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT00452218 |
Completed |
University of Chicago |
2012-05-31 |
| NCT00435331 |
6R-BH4 Pulmonary Arterial Hypertension Study |
https://ClinicalTrials.gov/show/NCT00435331 |
Completed |
Vanderbilt University |
2008-09-30 |
| NCT00433329 |
Combination Therapy in Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00433329 |
Completed |
Actelion |
2010-05-31 |
| NCT00423748 |
Study to Assess Safety and Efficacy of Ambrisentan in Subjects With Pulmonary Arterial Hypertension. |
https://ClinicalTrials.gov/show/NCT00423748 |
Completed |
Gilead Sciences |
NA |
| NCT00423202 |
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess Safety and Efficacy of Ambrisentan in Subjects With Pulmonary Arterial Hypertension. |
https://ClinicalTrials.gov/show/NCT00423202 |
Completed |
Gilead Sciences |
NA |
| NCT00367770 |
BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger Physiology |
https://ClinicalTrials.gov/show/NCT00367770 |
Completed |
Actelion |
2005-12-31 |
| NCT00323297 |
Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00323297 |
Completed |
Pfizer |
2013-08-31 |
| NCT00319267 |
Bosentan in Children With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00319267 |
Completed |
Actelion |
2006-12-31 |
| NCT00319020 |
Bosentan in Children With Pulmonary Arterial Hypertension Extension Study |
https://ClinicalTrials.gov/show/NCT00319020 |
Completed |
Actelion |
2011-10-28 |
| NCT00317486 |
Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology |
https://ClinicalTrials.gov/show/NCT00317486 |
Completed |
Actelion |
2005-04-30 |
| NCT00303459 |
Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT00303459 |
Completed |
Actelion |
2013-12-31 |
| NCT03556020 |
Phase 2 Study to Assess Safety, Tolerability and Efficacy of Once Weekly SC PB1046 in Subjects With Symptomatic PAH |
https://ClinicalTrials.gov/show/NCT03556020 |
Recruiting |
PhaseBio Pharmaceuticals Inc. |
2021-12-31 |
| NCT00257413 |
Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00257413 |
Completed |
Zhejiang University |
NA |
| NCT00159913 |
A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children With Pulmonary Arterial Hypertension. |
https://ClinicalTrials.gov/show/NCT00159913 |
Completed |
Pfizer |
2008-06-30 |
| NCT00159874 |
A Long Term Extension Study Evaluating Safety Of Sildenafil Citrate When Used To Treat Pulmonary Arterial Hypertension (PAH) In Children |
https://ClinicalTrials.gov/show/NCT00159874 |
Completed |
Pfizer |
2012-12-31 |
| NCT00105209 |
A Study of Aspirin and Clopidogrel in Patients With Idiopathic Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00105209 |
Completed |
Kawut, Steven, MD |
NA |
| NCT00086463 |
Trial of Iloprost Inhaled Solution as Add-On Therapy With Bosentan in Subjects With Pulmonary Arterial Hypertension (PAH) |
https://ClinicalTrials.gov/show/NCT00086463 |
Completed |
Actelion |
2006-01-31 |
| NCT00080457 |
Safety and Efficacy Study of Sitaxentan Sodium (Thelinâ„¢) in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00080457 |
Completed |
Encysive Pharmaceuticals |
NA |
| NCT00058929 |
A Transition Study From Flolan® to Remodulin® in Patients With Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00058929 |
Completed |
United Therapeutics |
2005-08-31 |
| NCT00004754 |
Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT00004754 |
Completed |
Office of Rare Diseases (ORD) |
NA |
| NCT00004497 |
Phase III Randomized Study of UT-15 in Patients With Primary Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT00004497 |
Completed |
FDA Office of Orphan Products Development |
NA |